Receptor abnormalities and diseases. 7. Myasthenia gravis and auto antibodies.

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Myasthenia Gravis and Associated Diseases

BACKGROUND Myasthenia gravis (MG) is an autoimmune disease caused by the action of specific antibodies to the postsynaptic membrane of the neuromuscular junction, leading to impaired neuromuscular transmission. Patients with MG have an increased incidence of other autoimmune diseases. AIM to determine the presence of other associated diseases in patients with MG. METHOD A group of 127 patie...

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Tissue-specific antibodies in myasthenia gravis.

Myasthenia gravis (MG) is a disorder of the neuromuscular junction characterised by weakness which increases on effort and is improved by rest and anticholinesterase treatment. Thymic abnormality with increased numbers of germinal centres is common, thymoma occurs in about 15% of cases, and thymectomy is often beneficial in thosewithoutatumour. The condition is commoner in women and typically b...

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Myasthenia gravis patients with anti-MuSK antibodies.

In myasthenia gravis (MG) patients without detectable anti-acetylcholine receptor (anti-AChR) antibody, referred to as seronegative myasthenia gravis patients, there is a variable proportion of patients with antibodies against the muscle-specific kinase (MuSK). MuSK antibodies were found in 8 (29.6%) of our 27 patients with generalized MG without anti-AChR antibodies. All these patients were fe...

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O 29: Autoimmune Myasthenia Gravis Introduction, Immunopathogenesis and Classification

Autoimmune Myasthenia Gravis (MG) is a unique disease among all autoimmune disorders in two ways. First, there are a wide range of sub-specialties involved in the diagnosis and management of MG; secondly MG is an autoimmune disorder whose autoimmunity is well established. In this paper I will cover these topics: history and epidemiology of MG followed by a brief overview on physiology of neurom...

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MYASTHENIA GRAVIS AND THYMECTOMY: A 10-YEAR STUDY IN SHIRAZ

A retrospective comparative study was performed on 54 patients treated medically or surgically (thymectomy) for myasthenia gravis (MG) from 1979- 1989 in three Shiraz University Hospitals. Each surgical patient was compared with a medical patient on the basis of age, sex, severity and duration of disease. Complete remission was noted in 3 out of 27 thymectomized patients but in none of the...

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ژورنال

عنوان ژورنال: Nihon Naika Gakkai Zasshi

سال: 1987

ISSN: 0021-5384,1883-2083

DOI: 10.2169/naika.76.1814